A widow, Deputy Sheriff Jane Kozik, moves from Manhattan to Black Stone, New York, with her daughter Kelsey. There she expects to find a safe place to live. The day after moving, a homeless man is found dead in the tool shed of Jane's blind friend Beverly; an entomologist, Katherine is summoned to help with the investigation, along with Devin, Jane's brother-in-law and former boyfriend. Meanwhile, Kelsey befriends Eli, a scientist who has developed genetically modified wasps to the army as a weapon, and who is now trying to revert the process. When the wasps attack Black Stone, Jane, Devin and Eli team-up to attempt to destroy the swarm.