José María Zavala returns to directing to produce the sequel to the feature film The Mystery of Padre Pío. On this occasion he will once again address the life of Saint Pio de Pieltrecina, a priest known for his miraculous gifts, both in life and post mortem. However, this second part is more focused on testimonials and more specific cases. Zavala will delve into the experience of 24 people, who, like him, were blessed by the religious, and who, according to what they say, as a result of that moment, their lives changed completely.