Louie and the Crew features the everyday life of a blue cubic feline with ears and a tail named Louie, who's best friends with Chris and Andy, which those two are the same species as him. They live in a fictional town called Swedeville (which is based on Sweden, but with 80% American and Canadian culture) and spend their days at school, clubs and convenience stores, but they have to deal with their biggest enemies — The Bulldogs (Brady, Boomer, Buster and Bill), cube-like bully dogs who pick on the three cat friends nearly every day. When Louie, Chris and Andy get together on screen, their lives are always risky and life changing.